Modern BCAA Product Details:An Exciting Breakthrough in BCAA Supplementation!
Rules For BCAA
We made it VERY clear to our R & D team -
USPlabs Modern BCAA MUST be developed under these strict rules:
- BCAA Ratio formulation with mTOR activation in mind
- Ultra-Micronized
- Must Mix Clean
- No Artificial Colors
- No Artificial Flavors
- GREAT taste
- No L-Glutamine
Little Known Anabolic Pathway - mTOR
If
you've never heard of mTOR (and even if you have), listen up and listen
good as this is one of THE most under-rated anabolic & protein
synthesis pathways known to man...And...chances are...you're not even
coming close to maximizing its enormous potential...
mTOR
(Mammalian Target of Rapamycin) is a large proline-directed
serine-threonine protein kinase that's responsible for a wide range of
physiologic and metabolic functions in several cell types, including
both adipocytes (fat cells) and myocytes (muscle cells)...
Among its
many roles, mTOR is responsible for hypertrophic growth (an increase in
muscle cell size, for example), protein synthesis and tissue
morphogenesis...
As a result, compounds which target the
regulatory pathways of mTOR have been highly sought out for quite some
time...A wide range of data have suggested that amino acids are capable
of directly regulating mTOR signaling pathways in skeletal muscle,
including the possibility that they activate some of the cell signaling
elements upstream from mTOR in the insulin/growth factor signaling
pathway...
Unlike Your Mom, mTOR DOES Play Favorites
However,
this same data suggest that the amino-acid induced activation of mTOR
signaling pathways is not uniform, and there is evidence that the
mechanism of mTOR activation may be both tissue and amino acid specific.
In particular, the amino acid leucine is indicated as being primarily
responsible for the branched chain amino-acid induced activation of mTOR
signaling pathways, and therefore mTOR's effect on protein turnover and
synthesis.
This hypothesis has come about as studies have shown
that most of the effects of amino acids on mTOR signaling are abolished
by lowering the concentration of leucine, or increased by adding leucine
and, to a lesser extent, the other branched-chained amino acids.
Leucine IS the Star...BUT...
In
other words, leucine is the star, but it also must be mentioned that
the other two BCAA's, isoleucine & valine, need to be present in
order to maximize results...
8-1-1 BCAA Ratio
With the
above in mind, we've formulated
USPlabs Modern BCAA with an 8-1-1
leucine-isoleucine-valine ratio...In terms of the leucine, the reasoning
here is that, from a strictly technical standpoint, the data displays
that only leucine and those other amino acids structurally related to
leucine are responsible for the increase in mTORcommonly associated with
BCAA supplementation.
Results & Value
As you know, many
people are doubling, tripling, even quadrupling their dosage of BCAAs
with a 2:1:1 & 4:1:1 bias in order to achieve better results...given
the fact that leucine is most likely the amino acid responsible for
this effect, particularly in skeletal muscle, having a formula with an
8:1:1 ratio eliminates the need for such increased dosing.
Effectively creating an enormous value in addition to the other benefits.
3 Man Enter - 1 Man Leave
The
other issue here is amino acid transport and metabolism. All three of
the branched chain amino acids - leucine, isoleucine and valine -
compete for the same transport systems, and as a result, the presence of
high concentrations of the other two branch-chained amino acids may
lower intracellular levels of leucine...obviously NOT what you want...
This
is further compounded by the fact that, once ingested, leucine first
fulfills other structural roles unrelated to protein metabolism prior to
activating mTOR signaling pathways. The result is that BCAA products
with a 2:1:1 or 4:1:1 bias may actually counteract the anabolic effects
from the product, as these substrates are pitted against one another to
compete for metabolism.
8-1-1 Rocks
By increasing the "normal" ratio of leucine to the other two branched chain amino acids, we ensure two things:
-
Double & mega dosing are unnecessary, as we have already doubled
the component that is primarily responsible for the protein turnover and
synthesis increases we see with BCAAs.
- Competitive metabolism between the amino acids will not lower leucine levels to the point that it is unable to regulate mTOR.
Simply
put, a 2:1:1 or 4:1:1 bias, while effective, is by no means optimal for
mTOR signaling pathway activation, and an increase in protein synthesis
associated with it.
Ultra-Micronized
Let's be honest -
when your uncle was rockin' his Zubaz & fannypack, he was drinking
the same bulky BCAA's that you're drinking right now. Sure, now there's
instantized BCAA's - but they are incredibly expensive & made by
using soy. And I know you're tired of BCAA "floaties" and losing
valuable product stuck to the side of the bottle. That's why the BCAA's
in USPlabs Modern BCAA utilize an advanced micronization process that
produces an incredibly light & voluminous powder that mixes great!
Plus,
USPlabs Modern BCAA will keep you on your game at the gym or at work -
no BCAA moustache or stained teeth to worry about...
Are You Drinking Ammonia?
Everyone
knows
creatine can quickly turn to its waste byproduct creatinine when
mixed in water. So why doesn't anyone ever talk about what L-Glutamine
can break down to?
Middle School Memories
Remember that
nasty ammonia smell when your middle school custodian was washing the
floors? You could just smell and taste the toxicity. I distinctly
remember walking into the locker room before Phys Ed class and the
freshly-applied ammonia felt like it was eating away my eye-balls...
I think it's safe to say we all have similar memories. No way you would ever drink that stuff, right?
WRONG!
That's
if you've been drinking L-Glutamine. L-glutamine is known for its
instability, in the dry state and especially in an aqueous solution. The
degradation products from L-glutamine can be glutamic acid, ammonia and
pyroglutamic acid, the latter two being potentially toxic.
What's worse is the longer it sits in water, the more degradation takes place!
Yuck!
Needless
to say, that's why we made it a rule that L-Glutamine was not in the
USPlabs Modern BCAA formula. Instead, to assist with blood glutamine
pools, we've included a compound called Sustamine...
Sustamine
This
particular product consists of a glutamine dipeptide
(L-alanyl-L-glutamine), which is more stable and far more water soluble
than regular L-glutamine.
These physicochemical properties alone
may provide greater effectiveness as compared to l-glutamine. However,
the presence of a unique intestinal transporter for the dipeptide may
also allow for an increased amount of glutamine to reach the bloodstream
and into skeletal muscle as compared to regular free L-glutamine (2-4).
These
notions are supported by the higher glutamine concentrations in plasma
and skeletal muscle of animal models administered alanyl-glutamine, as
compared to those observed with free L-glutamine.
This is important because up to 65% of regular L-glutamine can be destroyed before it makes its way to your muscles.
Would You Step Over a $20 Bill To Pick Up A Quarter?
As
mentioned, we added Sustamine to assist with blood glutamine pools, but
I want to make it abundantly clear we're not trying to win glutamine
product of the year here...
USPlabs Modern BCAA is a BCAA formula
first & foremost because, quite frankly, that's what delivers the
goods. If you want a bunch of ingredients that really won't have a
significant impact on your physique & performance, then USPlabs
Modern BCAA probably isn't for you. I mean, why run a 6 yard draw when
you can hit a 60 yard bomb over the top? If you want an awesome BCAA
product designed for those who truly realize just how important BCAA's
are, then USPlabs Modern BCAA was made with you in mind.
ZERO Artificial Colors & Flavors
This
is a hot topic as of late. In small amounts (such as those found in
capsules) there shouldn't be issues. It's when you get into powdered
products where the artificial colors & flavors start piling up -
often leaving you bloated, sluggish & generally not feeling your
best. Reason being, your body has no idea what to do with this stuff. It
can handle a small amount, but once you break a certain threshold, your
body simply cannot metabolize them.
Let's be honest, if your BCAA drink stains the inside of your cup, what do you think it's doing to the inside of your body?
And since we pound BCAA's like they're being pulled from the shelves, we simply couldn't put out a product that included them...
Unbelievable Taste
Yes,
I know, you've heard that one before - only to be disappointed... And
while taste is highly subjective, I'm incredibly confident you simply
won't believe you're drinking a naturally flavored BCAA product.
You'll want to drink it all day long!
Modern BCAA Supplement Facts:Serving Size: 2 Scoops (12.88g)
Servings Per Container: 35
Amount Per Serving:
Sodium 120mg 5%
Potassium 100mg 3%
Proprietary Blend 10g
Micronized L-Leucine, Micronized L-Isoleucine, Micronized L-Valine, L-Alanyl-LGlutamine (Sustamine)
Electrolyte Blend 662mg
Sodium Citrate, Potassium Chloride
Modern BCAA Other Ingredients:Citric Acid, Natural Flavors, Sucralose.
Modern BCAA Recommended Use:As a dietary supplement, mix 1 serving (2 level scoops) in 20 ounces of water and shake vigorously for 30 seconds. Sip throughout workout or athletic event.
An additional serving may be taken immediately after training or any time additional aminos are needed.
Using less than 10 ounces of water per scoop and/or very cold water can hinder solubility and cause foaming.
Due to high amino acid content some initial foaming may occur, which should subside over a few minutes time with light shaking.
Shake container before each use to disperse ingredients that may have settled.
Warning:
This product is only intended to be consumed by healthy adults 18 years of age or older. Pregnant or nursing women should not use this product. Discontinue use and immediately consult your health care professional if you experience any adverse reaction to this product. Do not exceed recommended serving. Do not exceed recommended serving. Do not use if safety seal is broken or missing. KEEP OUT OF REACH OF CHILDREN.